Relationship between dental caries and saliva’s visfatin levels, total antioxidant capacity (TAC) and total oxidant status (TOS)

Abstract Objectives Dental caries is a multifactorial infectious disease caused by the colonization and proliferation of bacteria in mouth. Recently, it has been reported that local antioxidant oxidant status may play an important role pathogenesis dental caries. Visfatin adipocytokine enhances leukocyte activation release proinflammatory cytokines. In this study, our aim was to investigate salivary visfatin levels, total capacity (TAC), (TOS) patients with without Methods Saliva samples were collected from 50 caries-free individuals 115 who admitted Selcuk University Restorative Dentistry Clinics. based on stimulated saliva collection procedure. levels measured using enzyme-linked immunosorbent assay. Spectrophotometric methods used determine TAC TOS. Results Salivary TAC, TOS, statistically higher compared group (p=0.035; p=0.003; p<0.001 respectively). There positive correlation between number TOS levels. Conclusions Findings prospective study demonstrated oxidative stress be involved visfatin, novel markers evaluate